Aminozide
1596-84-5
160.2
C6H12N2O3
DMF, DMSO, PBS (pH 7.2)
-20°C
Daminozide is a selective inhibitor of the KDM2/7 JmjC subfamily of histone demethylases. IC50=1.5, 0.55 and 2.1 μM for KDM2A, PHF8 and KDM7A respectively. Highly selective over other subfamily members (KDM3, KDM4, KDM5 and KDM6) as well as other 2-oxoglutarate oxygenases (FIH, PHD2 and BBOX1), IC50> 100 μM.
0.1 lbs
Research or further manufacturing use only, not for food or drug use.
